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John C. McDermott is a Full Professor in the Department of Biology at York University. He holds the McLaughlin Research Chair and is eligible to supervise the Biology Graduate Program. His research focuses on the basic regulatory mechanisms involved in cellular differentiation, particularly in cardiac, skeletal, and smooth muscle cells, as well as neurons. His work aims to understand the role of transcription factors in orchestrating tissue-specific gene expression during differentiation. McDermott has significantly contributed to identifying DNA binding proteins and understanding their role in transcriptional regulation associated with muscle development. He has explored the biological roles of the MEF2 gene family and their implications in cardiac and skeletal muscle differentiation in various post-natal contexts. His research, supported by the Canadian Institutes of Health Research (CIHR), has delved into growth factor-activated signaling pathways affecting key transcriptional regulators and the impact of MAP kinase pathways on MEF2 during embryogenesis. Additionally, McDermott's ongoing studies include the analysis of MEF2 interacting proteins using advanced Mass Spectrometry techniques.
Department of Liberal Arts & Professional Studies graduate programs generally follow the Faculty of Graduate Studies (FGS) B+ minimum requirement.