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John F. McDonald is a professor in the School of Biological Sciences at Georgia Institute of Technology. His research focuses on an integrated systems approach to the study of cancer, emphasizing the importance of understanding complex processes and the role of specific genes and proteins in cancerous cells. The McDonald lab employs high-throughput genomic technologies, such as DNA-seq, RNA-seq, and microarray analysis, to gather data on the status of cancer cells. The lab’s goals include the development of generalized cancer diagnostics through mass spectrometric metabolic profiling and the exploration of small non-coding RNAs as potential therapeutic agents, utilizing functionalized nanoparticles for targeted delivery to cancer cells. Additionally, McDonald investigates the significance of mRNA splice variants in the onset and progression of cancer. His work integrates strengths from engineering and computational sciences, fostering a cohesive research program that aims to advance our understanding and treatment of cancer.
Department of Computer Science: GRE scores are optional for Fall 2026.