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The Murray Lab focuses on developmental genetics, particularly investigating how genomes control animal development. By utilizing a model organism, the nematode Caenorhabditis elegans, the lab explores gene regulatory mechanisms and cell specialization that are analogous to human development. The research employs live-cell imaging, genomics methods, and classical genetics to understand gene regulation across various embryonic stages. The lab's contributions to the field include the lineage-resolved analysis of gene expression and comprehensive studies on mRNA decay within developmental contexts, providing insights into the differences in gene expression between cells during development. These efforts are aimed at deciphering the complex molecular pathways that govern both normal and aberrant development in multicellular organisms, enhancing our understanding of the fundamentals of life.
Murray Lab • Philadelphia, PA
Leading research on developmental genetics using C. elegans as a model organism.
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