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John Ngo is an Associate Professor in the Department of Biomedical Engineering at Boston University. He completed his PhD at the California Institute of Technology and received his BA from the University of California, Santa Barbara. His research primarily focuses on investigating the mechanisms of signal transduction at cell-cell interfaces, particularly through the Notch signaling pathway. His lab seeks to understand how mechanical tension is sensed by Notch receptors and its implications for protease sensitivity and signaling activities. Dr. Ngo's contributions to the field include developing methods to track de novo protein synthesis in neurons and tissues and probing cell mechanotransduction in health and disease. His work has been supported by notable grants from organizations such as the National Institutes of Health and the Adenoid Cystic Carcinoma Research Foundation. Through his leadership, students in his lab have received various awards, highlighting the impactful research being conducted at Boston University.
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