Dr. John Rose

Biography

John Rose earned his Ph.D. from Stanford University in 1973, under Dr. Charles Yanofsky, where his thesis research focused on the regulation of the tryptophan operon in E. coli. He completed postdoctoral research at the Massachusetts Institute of Technology in the laboratories of Drs. David Baltimore and Harvey Lodish, exploring eukaryotic RNA viruses. In 1978, Dr. Rose took a faculty position at the Salk Institute, where he continued his research on RNA virus transcription, structure, function, and the transport of the vesicular stomatitis virus (VSV) glycoprotein. In 1986, he became a Professor in the Department of Pathology and Cell Biology at Yale University School of Medicine. His laboratory has developed a methodology for recovering non-segmented, negative-strand RNA viruses from DNA plasmids and has significantly focused on new vaccine development approaches using vectors based on recombinant VSV viral replicons. His work has resulted in the creation of robust vaccine platforms, and notably, the VSV-based HIV vaccine developed by his laboratory has successfully completed a Phase clinical trial.

Research Interests

Experience

Awards