Dr. John Sedivy

Biography

Professor John Sedivy joined the Brown University faculty in 1996 as a member of the Department of Molecular Biology, Cell Biology, and Biochemistry. He obtained his PhD from Harvard in 1985 and trained under Nobel Laureate Philip Sharp at the MIT Center for Cancer Research. He began his independent research career at Yale University in 1988. His research has significantly focused on cell cycle regulation and signal transduction, beginning with the Myc oncogene and evolving into studies on replicative senescence, or cellular aging. Since 1989, he has been continuously funded by the National Institutes of Health. In 2003, he expanded his interests to genomics, contributing to bioinformatics and systems biology. Sedivy's lab has developed innovative single-cell assays to study cellular senescence and telomere-initiated senescence, leading to the delineation of signaling pathways associated with dysfunctional telomeres. He has published over 140 original articles and has served on numerous advisory committees for the NIH and other organizations. Sedivy has also consulted with multiple biotechnology firms and maintained an active role in aging research, chairing study sections and editing journals in the field. He has held leadership positions within Brown University, including chairing the Department of Molecular Biology, Cell Biology, and Biochemistry and founding the academic center for Genomics and Proteomics.

Research Interests

Experience

Awards