Dr. John Smeda

Biography

John Smeda is a Professor of Cardiovascular and Renal Physiology at Memorial University of Newfoundland, holding a B.Sc.(Hons.) and M.Sc. from Brock University and a Ph.D. from McMaster University. His research focuses on the pathophysiology of hemorrhagic stroke, particularly utilizing animal models to elucidate the mechanisms underlying cerebrovascular function. Smeda's work has shown that the administration of captopril, an angiotensin-converting enzyme inhibitor, can significantly extend the lifespan of stroke-prone hypertensive rats. His studies reveal that captopril not only lowers levels of angiotensin II and aldosterone but also helps restore the cerebrovascular response to blood pressure changes, which is crucial for preventing recurrent strokes. Smeda has published extensively on these topics, contributing valuable insights into the neuro-hormonal interactions that affect cerebral blood flow and potential therapeutic interventions for stroke victims.

Research Interests

Experience