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Professor Jon Lane specializes in Cell Biology at the University of Bristol. His research focuses on autophagy and the cellular responses to stress. His group utilizes transformed human cells and human induced pluripotent stem cells (hiPSCs)-derived neurons and glia to study how autophagy influences neuronal resilience in conditions like Parkinson's disease. Professor Lane's academic path includes earning a B.Sc. in Biology from Southampton University, followed by a Ph.D. at Exeter in cell cycle regulation and microtubule dynamics. His postdoctoral work in Manchester explored developmental microtubule motor control and the effects of organelle disruption on protein trafficking and apoptosis. With the support of a Wellcome Trust Career Development Fellowship, he established his research group at Bristol, where he has been advancing his studies on the crucial roles of autophagy in various human diseases, emphasizing its impact on neuronal health through membrane trafficking dynamics. His lab employs techniques such as live-cell imaging and electron microscopy to analyze autophagosome assembly and function within cell lines.
University of Bristol • Bristol, England
Professor in Cell Biology focusing on autophagy and its influence on neuronal resilience.
Department of Physics research themes include Astrophysics, Materials and Devices, Particle Physics, and Quantum and Soft Matter.