Dr. Jon Levine

Biography

Jon Levine is a Professor and Director of the Wisconsin National Primate Research Center at the University of Wisconsin–Madison. His research focuses on neuroendocrine regulation of reproduction and metabolism, particularly the actions of steroid hormones on brain behavior. He investigates the cellular mechanisms that mediate the physiological regulation of gonadotropin-releasing hormone (GnRH) neurosecretion during the female ovulatory cycle. His studies utilize a variety of experimental approaches and animal models to ascertain the molecular processes influenced by gonadal steroids, diet, stress, and neuroendocrine signals on sexual maturation and GnRH release. Levine's work emphasizes the impact of reproductive metabolic disorders, such as polycystic ovarian syndrome (PCOS), on the neural circuits controlling GnRH release, leading to infertility when feedback control mechanisms fail. Through his research, he aims to enhance understanding of the cellular basis of PCOS pathophysiology and examine the early developmental factors contributing to its manifestation. Ultimately, he seeks to provide novel insights into the mechanisms through which steroid hormones govern reproductive physiology, neural development, and behavior.

Research Interests

Experience