Professor Dr. Jonathan Henninger

Biography

Jonathan Henninger is an Assistant Professor in the Department of Biological Sciences at Carnegie Mellon University. His research focuses on developmental regenerative biology, particularly on the mechanisms by which RNA regulates cell fate in health and disease. The Henninger lab investigates how active genes are influenced by crowded RNA molecules that participate in gene regulation. The lab employs a combination of molecular biology techniques, soft-matter physics, and super-resolution imaging to explore the interactions that RNA molecules have as scaffolds for large assemblies of proteins involved in transcription and RNA processing. Through this research, Henninger aspires to uncover fundamental mechanisms behind gene control and to inspire the development of new RNA-based therapies, aiming to better understand how RNA defects contribute to human disease.

Research Interests