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Professor Jonathan Morris is Dean of Research and Enterprise at the Graduate Research School. His research interests are focused on the development of organic molecules for use in biomedical research, particularly the application of natural products as biomedical agents. These natural products provide novel leads for pharmaceuticals across a diverse array of therapeutic areas, presenting excellent starting points for medicinal chemistry programs. Prof. Morris works on addressing the bottlenecks in the development of natural products resulting from limited availability of compounds. His major focus is on developing small molecules that modulate alternative splicing of RNA, which has significant therapeutic potential for conditions such as age-related macular degeneration and cancer pain management. A key aspect of his research involves the total synthesis of rare alkaloids, facilitating the discovery of potent kinase inhibitors that control alternative splicing processes. This work has led to the investigation of new treatments for eye diseases in collaboration with industry partners.
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