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Joost Martens is an Associate Professor in Molecular Biology at Radboud University. His research focuses on recurring chromosomal abnormalities identified in various cancers, particularly the associations with hematological malignancies such as acute myeloid leukemia (AML). His main goal is to unravel the role of oncofusion proteins in carcinogenesis. Martens aims to identify binding regions and transcriptional consequences, along with epigenetic features associated with oncofusion protein expression. He employs next-generation sequencing and high-resolution transcription factor epigenomic profiling to identify oncofusion protein target sites and characterize their structural and functional implications on the etiology of acute myeloid leukemia using molecular bioinformatics tools. His work contributes significantly to understanding normal and aberrant hematopoietic development.
Applies to Research Master's in Linguistics and Communication Sciences (Centre for Language Studies/Department of Language and Communication).