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Jörn Dengjel is a researcher in the Department of Biology at the University of Fribourg, where he explores the molecular mechanisms of autophagy and its implications in cellular metabolism and cancer. His work focuses on the regulation of autophagy through post-translational modifications, specifically the roles of protein kinases and phosphatases in cellular stress responses. Dengjel has conducted significant research on selective autophagy and metabolic reprogramming, utilizing advanced mass spectrometry techniques. He has developed innovative in vitro models to replicate human tumor environments for cancer therapy studies and has published extensively on the subject, contributing valuable insights essential for therapeutic advancements against diseases like cancer and neurodegeneration. His ongoing projects include studying interactions within autophagy regulatory complexes and broadening the understanding of autophagy's role in maintaining cellular homeostasis. Dengjel contributes to the academic community through mentorship and teaching, further advancing the field of biology.
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