Dr. Joseph Madri

Biography

Joseph Madri is a Professor Emeritus at Yale School of Medicine specializing in Pathology. His research interests primarily focus on endothelial cell dynamics, specifically the interactions that dictate vasculogenesis and angiogenesis. His laboratory investigates signaling pathways related to endothelial cell adhesion and their modulation by extracellular matrix components and various cell adhesion molecules like PECAM-1 and CD44. Dr. Madri's influential work has elucidated critical mechanisms of endothelial cell behavior and its implications in the context of inflammation, repair, and disease. Current projects include exploring T cell interactions with endothelial cells and the molecular pathways activated during these processes, especially under hypoxic conditions commonly observed in premature infants. Madri’s research employs a combination of animal models and advanced imaging techniques to reveal the roles of endothelium in developmental disorders and tissue repair processes. His contributions also extend to investigating the underlying mechanisms connecting premature birth and neurodevelopmental challenges.

Research Interests

Experience

Awards