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Joseph O'Connor conducts research that encompasses areas of organic chemistry, bioorganometallic chemistry, and synthetic mechanistic chemistry. His ongoing projects explore the interface between organic molecules and biological applications, aiming to develop new organometallic triggering mechanisms for drug delivery. His team is synthesizing novel organometallic DNA cleavage agents that utilize metals to stabilize reactive organic enediyne molecules for targeted biological applications. O'Connor's research also emphasizes the development of new synthetic methodologies, specifically in the field of metallacyclobutene chemistry, which are crucial intermediates in a variety of metal-catalyzed reactions. He tackles challenges in carbon-sulfur bond activation and engages in the theoretical aspects of catalysis, focusing on novel transformations that have broad implications in chemical sciences and pharmaceuticals. O'Connor actively participates in outreach to underrepresented minority scholars, mentoring them through various programs and initiatives at UC San Diego, contributing to the diversity and inclusion in scientific academia.
Administered by the Scripps Institution of Oceanography. Curricular groups include Climate-Ocean-Atmosphere (COAP), Geosciences (GEO), and Ocean Biosciences (OBP).