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Joseph Pogliano is a professor specializing in the evolution of the microbial cytoskeleton. His research focuses on understanding how prokaryotic cells establish and maintain their complex subcellular organization, particularly through the study of cytoskeletal proteins. His laboratory works on identifying and characterizing key families of dynamic cytoskeletal proteins in bacteria and determining their functions and regulation. The lab employs genetic and cell biological approaches to study the assembly and dynamics of cytoskeletal polymers in various prokaryotic species, including Escherichia coli and Bacillus subtilis. Their research has led to groundbreaking discoveries, including new types of cytoskeletal structures involved in DNA segregation and novel families of tubulins and actins. Pogliano's work aims to provide insights into both prokaryotic cellular organization and the evolutionary origins of the eukaryotic cytoskeleton through collaborative efforts with biochemists and structural biologists. His lab is recognized for its innovative use of plasmids as tools to explore the genetic diversity and complexity of cytoskeletal polymers.
Administered by the Scripps Institution of Oceanography. Curricular groups include Climate-Ocean-Atmosphere (COAP), Geosciences (GEO), and Ocean Biosciences (OBP).