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Joseph Schlessinger is the William H. Prusoff Professor of Pharmacology at Yale School of Medicine. His research focuses on the critical roles of tyrosine phosphorylation in cellular processes such as cell proliferation, differentiation, metabolism, survival, and migration. He has extensively studied receptor tyrosine kinases (RTKs), elucidating their mechanisms through various structural studies, including the determination of crystal structures for several key complexes. Schlessinger's work has significantly advanced the understanding of how RTKs interact with ligands and the molecular pathways that lead to cellular responses, which are crucial in cancer research. He is also involved in the development of new inhibitors targeting protein tyrosine kinases that are currently undergoing clinical trials, showcasing his dedication to translating fundamental research into therapeutic applications. Throughout his career, he has received numerous awards for his contributions to cancer research and is recognized as a leading figure in his field.
Administered via the Graduate School of Arts and Sciences (GSAS). GRE General is optional for PhD.