Dr. Joseph Wider

Biography

Dr. Joseph Wider is a Research Assistant Professor at the University of Michigan Medical School in the Department of Emergency Medicine. His research focuses on the role of mitochondria in brain function and their dysfunction in relation to acute brain injuries such as traumatic brain injury, ischemic stroke, and cardiac arrest. Dr. Wider’s lab employs various preclinical and translational models to understand the molecular mechanisms of mitochondrial dysfunction and its causal relationship with brain injury pathogenesis. He is particularly interested in how mitochondrial dynamics, mitophagy, and biogenesis affect energy production in the brain, which relies exclusively on oxidative phosphorylation. The lab is also developing targeted therapeutics aimed at mitochondrial function to improve neurological outcomes in acute brain injury. Dr. Wider holds a PhD from Wayne State University in Emergency Medicine and has been involved in significant research regarding mitochondrial dynamics and cellular dysfunction in brain injury. He has contributed to various publications that highlight his ongoing work and findings in the field.

Research Interests

Experience