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Juan R. Alvarez is an Assistant Professor in the Department of Cell Developmental Biology at the Perelman School of Medicine, University of Pennsylvania. He obtained his B.A. in Molecular Biology from Princeton University in 2009 and earned his Ph.D. in Biology from the Massachusetts Institute of Technology in 2015. Dr. Alvarez's research focuses on understanding how biological rhythms influence the functional maturation of differentiated cells, specifically in the context of pancreatic islet development and regenerative medicine. His laboratory employs advanced techniques such as genetic engineering and single-cell omics to investigate the interplay between circadian biology and cell maturation, with the ultimate goal of developing insulin-dependent diabetes therapies using engineered pancreatic islet organoids. His work addresses critical questions about cellular specialization and how organ-level physiology can be synchronized with circadian rhythms to prevent metabolic dysfunction.
Perelman School of Medicine, University of Pennsylvania • Philadelphia, PA
Conducting research in cell developmental biology, focusing on pancreatic islet development and regenerative medicine.
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