Dr. Judith Campbell

Biography

Judith L. Campbell is a Professor at the California Institute of Technology, specializing in Biochemistry and Molecular Cell Biology. Her research addresses the mechanisms of DNA replication and repair, focusing on how these processes are disrupted in cancer cells. She employs various model systems, including yeast genetics and human cell extracts, to study the DNA replication apparatus and its regulation, particularly examining the roles of helicases like Dna2. Her laboratory investigates the biochemical pathways that underlie genomic stability and the response to DNA damage, with a specific interest in understanding how aberrations in these pathways contribute to cancer predisposition and aging. Campbell’s work also includes the study of telomeres, recognizing their crucial role in the maintenance of chromosome integrity during cell division, and how the dysfunction of proteins like Dna2 can lead to significant cellular outcomes, such as increased rates of genomic instability or premature aging. Over the years, she has published extensively on these topics, contributing to our understanding of the fundamental processes that sustain cellular life and how their failure can lead to disease.

Research Interests

Experience