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Judith N. Mandl is an Associate Professor in the Department of Physiology at McGill University, specializing in Immunology and Molecular & Cell Biology. Her research focuses on T cells and their crucial role in immune protection, particularly regarding their specificity for antigens and the processes involved in T cell receptor diversification and response initiation. Mandl's studies investigate T cell trafficking, interactions with self-peptides presented by Major Histocompatibility Complex (MHC) molecules, and the perturbations that can lead to immunodeficiency and altered immune responses. Her lab employs advanced techniques such as 2-photon intravital multi-parameter confocal microscopy to examine the dynamic behavior of T cells in complex tissues. Through this research, she aims to develop new therapies for treating immunological diseases. Dr. Mandl received her Ph.D. from Emory University and completed her postdoctoral training at the National Institutes of Health.
Department: Department of Medicine. Program: Experimental Medicine.