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Judith Simcox is an Associate Professor in the Department of Biochemistry at the University of Wisconsin-Madison. She is recognized as an HHMI Freeman Hrabowski Scholar. Her research focuses on metabolism and endocrinology, particularly examining inter-organ communication and the role of lipid-derived metabolites in thermogenesis. Her work investigates the processes involved in the utilization of lipids as metabolic fuels, especially in brown adipose tissue. Simcox's laboratory aims to understand how lipids drive thermogenesis and the regulatory pathways involved. She utilizes lipidomics, genetics, and cellular and molecular biology techniques, alongside mouse physiology, to address questions regarding lipid metabolism and thermoregulation. During her postdoctoral training, Simcox discovered that acylcarnitines are essential for maintaining body temperature during cold exposure, an area that continues to inspire her research. Her long-term research program seeks to uncover the mechanisms through which cold exposure affects lipid metabolism and thermogenesis, making significant contributions to understanding metabolic diseases such as obesity and type 2 diabetes.
Department: Department of Computer Sciences