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Jueqi Chen is an Assistant Professor in the Biological Sciences Division at the University of Chicago. His research focuses on the molecular mechanisms of inflammasome pathways and their dysfunction in response to pathogenic microorganisms. Specifically, his lab studies the innate immune signaling triggered by various elements including pathogens and environmental dangers. The laboratory employs a range of techniques including biochemical assays, confocal fluorescence imaging, and CRISPR gene editing to investigate inflammasome activation and its implications in disease processes, including autoimmune disorders and neurodegeneration. Chen's work has revealed important insights regarding the role of the trans-Golgi network in inflammasome activation, and he continues to explore how pathogens can evade immune responses and what this means for human health. He is particularly interested in identifying therapeutic targets for infectious diseases.
Department of Philosophy