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Jumi Shin is an Associate Professor in the Department of Chemistry at the University of Toronto Mississauga. Her research focuses on Analytical Chemistry, Biological Chemistry, and Organic Chemistry. The Shin lab leverages building blocks from nature, such as proteins and nucleic acids, to address challenges in human health and environmental ecosystems. Her team designs small proteins that can bind to specific DNA targets to regulate gene expression, with particular attention to cancers. The lab utilizes various spectroscopic methods such as fluorescence resonance energy transfer (FRET), anisotropy, circular dichroism, and x-ray crystallography in their analysis of protein structure and function, alongside biological assays involving yeast and bacterial one-hybrid systems, testing on cancer cell lines and mouse models. Research additionally examines the role of nanomaterials, which are prevalent in many aspects of daily life including electronics and coatings, and their impact on organisms and environmental evolution. Employing a multidisciplinary approach that combines quantitative genetics, nano-engineering, and molecular biology, Dr. Shin investigates how chronic exposure to nanomaterials may lead to genetic mutations in organisms in their quest for survival.
Department of Sociology