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Junqin Bai, PhD, is a Research Assistant Professor in the Department of Otolaryngology–Head & Neck Surgery at Northwestern University Feinberg School of Medicine. Dr. Bai's expertise lies in translational biology and immunology, focusing on the intersection of patient-derived multi-omics data and clinical decision-making related to chronic rhinosinusitis and nasal polyps (CRSwNP). Her research is centered on understanding B-cell activation, differentiation, and epithelial–immune crosstalk while integrating various modern technologies such as single-cell RNA sequencing (scRNA-seq), bulk transcriptomics, and advanced analytics to identify therapeutic targets and predictive biomarkers of polyp recurrence and disease severity. Dr. Bai has developed a clinically validated polyp-recurrence risk score that helps stratify patients according to their risk over time, supporting personalized follow-up therapy selection. Additionally, her ongoing clinical trial work examines the mechanisms of olfactory loss associated with CRSwNP and profiles olfactory epithelial cells and protein targets in nasal secretions. Beyond her primary research, she is involved in collaborative projects that investigate the role of mast cells and eosinophils in the progression of eosinophilic esophagitis (EoE).
Administered by The Graduate School; focuses on Biomechanics, Imaging, Biomaterials, and Regenerative Medicine.