Dr. Karen Reddy

Biography

Karen L. Reddy is an Associate Professor in the Department of Biomedical Engineering at Johns Hopkins University. She received her PhD from the University of Illinois in 2002. Her research interests focus on understanding how nuclear periphery subcompartments contribute to general nuclear architecture and specific gene regulation. Reddy's work investigates the cell biology of genomes and how their nuclear architecture controls gene expression, which is essential for understanding the biological processes underlying development and disease. Through sequencing and comparative genome analysis, Reddy aims to gain insights into the regulation and deregulation of genetic information. Her research efforts are aimed at elucidating how the architectural organization of cellular genomes relates to gene activity, which is a crucial step in unlocking the genetic and epigenetic mechanisms involved in development and disease pathology. In her lab, she specifically seeks to understand the genes regulated at the nuclear periphery, deciphering how genes are localized to specific nuclear compartments and determining the processes involved when these mechanisms are corrupted by disease.

Research Interests