Dr. Karl Dimiter Bissig

Biography

Karl-Dimiter Bissig is the Chen Family Associate Professor in the Department of Pediatrics at Duke University. His research focuses on liver diseases including viral hepatitis, metabolic liver disorders, and liver cancer. He leads a lab that specializes in human liver chimeric mice and has developed xenograft models for studying metabolic liver diseases as well as novel patient-derived cancer models. His work utilizes humanized mouse models to develop new therapeutic approaches and explores metabolic pathway reprogramming using CRISPR-based gene therapy. With an MD and PhD from the University of Bern in Switzerland, Dr. Bissig has completed his medical residency in Internal Medicine at Inselspital and conducted postdoctoral research at the Salk Institute for Biological Studies. He has held multiple associate professorships in Pediatrics, Biomedical Engineering, and Pharmacology Cancer Biology, and is also a member of the Duke Regeneration Center and the Duke Cancer Institute.

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