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Karl-Dimiter Bissig is the Chen Family Associate Professor in Pediatrics at Duke University School of Medicine and an affiliate of the Duke Regeneration Center. He specializes in the study of liver diseases, with particular focus on viral hepatitis, metabolic liver disorders, and liver cancer. His laboratory is pioneering research on human liver chimeric mice, creating xenograft models to better understand metabolic liver diseases and develop new therapeutic strategies. Furthermore, he utilizes humanized mouse models for the generation of innovative therapeutic approaches, including CRISPR-based gene therapy methods. Bissig's expertise spans both clinical and translational research, with a strong emphasis on metabolic pathway reprogramming, ultimately aiming to improve treatment outcomes for patients with liver diseases.
Duke University School of Medicine • Durham, NC
Duke University School of Medicine • Durham, NC
Duke University Pratt School of Engineering • Durham, NC
Duke University School of Medicine • Durham, NC
Salk Institute Biological Studies • La Jolla, CA
Department of Biomedical Engineering (MS program)