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Karuna Ganesh is an Assistant Member and Medical Oncologist at the Sloan Kettering Institute. His research focuses on the molecular mechanisms underlying the emergence, persistence, and therapy resistance of metastatic cancer. The Ganesh Lab employs advanced methodologies such as patient-derived organoid and mouse models of colorectal cancer, alongside transcriptomic, epigenomic, and single-cell analyses. Their goal is to elucidate tumor behavior, particularly how cells invade and disseminate, and the roles played by stromal and immune cells in the context of metastatic cancer. Additionally, Ganesh collaborates with clinicians to better understand therapy resistance mechanisms. He completed his medical training and PhD at the University of Cambridge in the UK, where he developed a strong foundation in molecular pharmacology. His work has significant implications for developing therapeutic strategies targeting the vulnerabilities of metastatic cancers.
Sloan Kettering Institute • New York, NY
Engaged in research focused on understanding the mechanisms of cancer metastasis and therapy resistance.
Administered through the Gerstner Sloan Kettering (GSK) Graduate School. The program focus is Cancer Biology and includes faculty from the Department of Molecular Pharmacology.