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Associate Professor Kate Poole works in the School of Biomedical Sciences at UNSW Sydney, focusing on how cells sense and respond to mechanical inputs. Her research primarily investigates two main streams: characterizing the force-sensing abilities of cancer cells and understanding cellular behavior in microgravity conditions. Poole's work has revealed how mechanical properties of tissues, such as the stiffening observed in tumor environments, impact disease progression, particularly in cancer. Her research team seeks to unravel the molecular mechanisms of force-sensing in cancer cells, aiming to identify new molecules that influence cell migration during metastatic processes. Additionally, she explores how microgravity affects cellular functions, maintaining health in reduced gravity environments, such as those experienced by astronauts. By addressing these critical issues, Poole aims to improve human health and performance in space.
University of New South Wales • Sydney, Australia
Leading research on cell mechanosensing and its implications in cancer biology and microgravity.
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