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Katherine Gaulton leads the Gaulton Lab at the University of California San Diego School of Medicine, focusing on understanding the genetic and environmental risk factors for type 1 diabetes (T1D) and other complex diseases. The lab employs cutting-edge techniques in single-cell epigenomics and population genetics to explore gene regulatory programs and regulatory networks that influence disease risk. By using single-cell methods to characterize epigenomes across various human tissues, the lab aims to identify novel biomarkers that improve risk prediction and therapeutic strategies. The Gaulton Lab has made significant contributions to the field, including generating the largest genome-wide association study (GWAS) for type 1 diabetes to date and developing machine learning genetic risk scores for assessing complexity in disease cases. Furthermore, they are actively involved in collaborative efforts that improve access to scientific data and resources, ensuring their findings can benefit the wider research community. Overall, the lab strives to enhance personalized medicine approaches through meticulous identification of therapeutic targets and biomarkers related to T1D.
Gaulton Lab, University of California San Diego • La Jolla, CA
Leading research efforts focused on genetic and environmental contributors to type 1 diabetes.
Administered by the Scripps Institution of Oceanography. Curricular groups include Climate-Ocean-Atmosphere (COAP), Geosciences (GEO), and Ocean Biosciences (OBP).