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Kathrin M. Bernt, MD, is an Associate Professor in the Department of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania. She specializes in Pediatric Hematology/Oncology, focusing on the molecular mechanisms underlying pediatric hematologic malignancies. Dr. Bernt's research aims to understand the 'molecular makeup' of leukemia to develop targeted therapies, particularly emphasizing epigenetics and transcriptional regulation. Her lab utilizes a wide range of models, including genetically engineered murine and retroviral models, patient samples, and cell lines, to explore various leukemogenic drivers and their roles in leukemia development. Funded by the National Cancer Institute and other institutions, her work addresses significant mutation pathways, including IDH mutations and the involvement of MN1 fusions in leukemia. Dr. Bernt's dedication to uncovering these mechanisms aims to lead to novel therapeutic strategies for improving patient outcomes in children and adults suffering from these malignancies.
Perelman School of Medicine, University of Pennsylvania • Philadelphia, PA
Teaching and conducting research in Pediatric Hematology/Oncology.
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