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Kathy Fange Liu, Ph.D. is an Associate Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania. Her research focuses on enzymes that regulate gene expression in both normal physiology and cancer biology. Dr. Liu's lab investigates unique biochemical mechanisms that underlie cancer vulnerabilities, aiming to combine in-depth mechanistic studies with innovative therapeutic development. Her work encompasses several key areas including X-Y paired homologous proteins, cancer fusion proteins, ribosome biology, and the co-regulation of enzyme-mediated modifications of RNA species. The overarching goal of her research is to redefine the molecular understanding of cancer, which can lead to new treatment avenues and bridge fundamental biochemistry with translational research. Dr. Liu aims to forge a direct path from benchside discoveries to impactful clinical applications, fundamentally changing the approach to cancer treatment.
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