Dr. Keaton Jones

Biography

I graduated with Honours in Medicine from Nottingham University in 2011. My research career began with an Academic Foundation position supervised by Professor Jon Lund at the University of Nottingham. I was subsequently appointed as an NIHR Academic Clinical Fellow at the University of Oxford, where I completed my basic surgical training. In 2015, I undertook a DPhil (PhD) in Oncology under the supervision of Professor Ruth Muschel at the CRUK/MRC Department of Oncology, University of Oxford. My thesis explored the tumour immune response to radiotherapy in preclinical models of colorectal and pancreatic adenocarcinoma. In 2020, I took a position as an NIHR Clinical Lecturer in the Nuffield Department of Surgical Sciences, where I investigated the role of PI3K-gamma in pancreatic cancer macrophages. In 2025, I received the Wellcome Trust Early Career Award to investigate the role of macrophage metabolism in determining therapeutic responses in pancreatic cancer. My research aims to identify and test novel therapies for individuals suffering from pancreatic cancer, utilizing high fidelity models to examine how tumours respond to treatments, and identifying mechanisms of resistance to render pancreatic cancer more susceptible to both conventional and novel therapies.

Research Interests

Experience