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Dr. Brunt's laboratory focuses on translational medicine with a major interest in understanding how cells adapt to stress, developing innovative therapeutic strategies to treat diseases. His active research projects include Discovery Science, which emphasizes understanding the molecular regulation of heme metabolism and basic molecular mechanisms related to health, aging, and disease. The lab is also involved in Patient-Tailored Theranostics, assessing pre-clinical pharmacodynamics of site-directed biomimetic nanoparticles for the delivery of small molecules, biologics, or gene therapy in a disease-specific manner. Research on Healthy Aging investigates the molecular mechanisms of aging and their implications for patients, particularly in stem cell therapy and regenerative medicine. Additionally, Dr. Brunt's work in Medical ICT aims to translate advances in medical and information-communication technologies to improve patient outcomes and prevent adverse drug reactions.