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Keith Channon is a leading researcher in Cardiovascular Medicine, currently serving as the Field Marshal Earl Alexander Professor at the Radcliffe Department of Medicine, University of Oxford. His primary research interests include nitric oxide signalling and its role in cardiovascular diseases. He focuses on understanding the early changes in the endothelium and vascular wall that relate to the initiation and development of vascular diseases. His work investigates the abnormalities associated with diabetes, high cholesterol, smoking, and high blood pressure that impact endothelial function. Channon explores the regulation of nitric oxide synthase enzymes and their interactions with reactive oxygen species, which are crucial for maintaining the health of blood vessel walls. He has developed transgenic models to manipulate tetrahydrobiopterin levels and has carried out clinical trials to assess treatments aimed at improving endothelial function by enhancing these levels.
Department of Politics and International Relations - Higher Level English requirement.