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Dr. Frazer is an internationally renowned leader in the field of genome biology and medicine. She is the director of the UC San Diego Institute for Genomic Medicine and the founding chief of the Division of Genome Information Sciences in the Department of Pediatrics at UC San Diego. The Frazer Lab utilizes approaches such as the iPSCORE (induced Pluripotent Stem cell Collection for Omics Research), which is a collection of iPSC lines derived from human adult cells intended for studying genetic variants associated with human molecular phenotypes. Over the past nine years, her lab has developed a unique collection of iPSC lines from 222 individuals, which allows for systematic analysis of genetic variants affecting human disease. The lab employs techniques like genotype-molecular phenotype correlations pertinent to various derived cell types, including cardiomyocytes and pancreatic precursor cells. The Frazer Lab is also involved in the Center for Admixture Science and Technology (CAST), focusing on the interplay between genetics, behavior, and environmental factors influencing health, with collaborative efforts to identify new genes involved in inherited retinal dystrophies.
Administered by the Scripps Institution of Oceanography. Curricular groups include Climate-Ocean-Atmosphere (COAP), Geosciences (GEO), and Ocean Biosciences (OBP).