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J. Kevin Foskett is an Isaac Ott Professor in the Department of Physiology at the Perelman School of Medicine, University of Pennsylvania. His research focuses on the molecular physiology and pathophysiology of inositol trisphosphate receptors, which play a crucial role in intracellular calcium signaling. His lab employs a variety of techniques including biophysics, molecular biology, and electrophysiology to understand the signaling mechanisms involved in cellular processes. Foskett is particularly interested in how alterations in calcium signaling can lead to diseases such as Alzheimer's and cystic fibrosis. Over the years, he has contributed significantly to the understanding of mitochondrial calcium uptake and its implications for bioenergetics in neurodegenerative diseases. His work has resulted in numerous influential publications, and he is recognized as a leading figure in the field.
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