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Dr. Koseki Kobayashi-Kirschvink is an Assistant Professor at the University of Chicago in the Biological Sciences Division. He leads an interdisciplinary research group that integrates physics and machine learning with genomics to investigate dynamic biological processes at single-cell resolution. His lab is focused on developing new optical molecular tools that reveal how cells self-organize into complex multicellular structures, such as tissues and embryos, and elucidate the function of immune cells in tumor microenvironments. Central to his group's research is the 'live-cell omics' approach, which measures genome-wide expression in living single cells, an achievement not possible with conventional omics methods. His methodologies enable longitudinal tracking of genomic changes in individual cells, shedding light on the molecular mechanisms of cell fate determination and disease progression. Additionally, his lab builds next-generation, label-free microscopes that reduce the acquisition time of conventional instruments, thus facilitating large-scale studies of molecular dynamics in both vitro and vivo scenarios.
Department of Philosophy