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Kyle Biggar is an Associate Professor in the Department of Biology at Carleton University, specializing in functional proteomics. His research focuses on the reversible modifications of proteins known as post-translational modifications (PTMs), particularly lysine methylation, which is crucial in regulating protein-protein interactions and cellular functions. His laboratory investigates how proteins interact with enzymes to select substrates and the role of these interactions in cellular signaling and regulatory networks, especially in relation to disease progression and treatment resistance. Biggar employs advanced biochemical and molecular biology techniques, including the synthesis of custom peptide arrays and functional proteomic technologies, to screen protein-protein and enzyme-substrate interactions. Students working in his lab gain valuable hands-on experience with both basic and advanced cellular biochemical methods, alongside opportunities for interdisciplinary collaboration. Biggar's work has been published in several reputed journals, reflecting his significant contributions to the field of protein research.
Includes MEng and MASc options.