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Lachlan Smith leads a translational spine joint research laboratory at the University of Pennsylvania, focusing on the pathophysiology and treatment of degenerative and developmental disorders affecting the spine and synovial joints. His research encompasses a wide range of studies including basic mechanistic research, translational studies in animal models, and clinical studies involving human patients. Employing cutting-edge techniques in molecular biology, biochemistry, and bioengineering, he creates novel in vitro model systems to investigate disease mechanisms. Dr. Smith aims to bridge the research in tissue engineering, biomaterials, drug delivery, and stem cells, focusing on halting disease progression, restoring spine function, and enhancing long-term tissue regeneration. His multidisciplinary team includes biologists, bioengineers, clinicians, and veterinarians, working together to evaluate therapeutics using novel, naturally occurring inducible large and small animal models for studying disease etiology. His research program is funded by the National Institutes of Health, the Department of Veterans Affairs, as well as numerous private foundations and benefactors.
Wharton Doctoral programs cover fields like Finance, Marketing, Management, and Operations, Information and Decisions.