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Professor Lars Jansen's research focuses on chromatin, the complex of DNA and proteins that packages DNA into structural units known as nucleosomes. His lab investigates mechanisms of chromatin inheritance and how chromatin structures maintain gene expression over mitotic and meiotic divisions. This work aims to elucidate the processes of self-templated duplication during synchronized cell division, particularly as it pertains to the human centromere's role in connecting chromosomes to the mitotic spindle. Additionally, Jansen explores long-term transcriptional memory in human cells, and how chromatin plays a critical role in the epigenetic maintenance of gene expression. His research has implications for understanding epigenetic mechanisms and heritable gene expression in evolutionary adaptation, with a particular interest in yeast populations.
Department of Politics and International Relations - Higher Level English requirement.