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Laura Machesky is a professor in the Department of Biochemistry at the University of Cambridge. Her research focuses on cell migration, actin dynamics, and cancer metastasis. Machesky investigates how cells adapt their cytoskeletons and energy flux to invade complex environments, which is crucial for understanding the metastasis of solid tumors. One of her significant contributions to the field includes the discovery that pancreatic cancer cells can sense the stiffness of their environment and adjust their migration accordingly. Her work also explores how cellular metabolic machinery interacts with the cytoskeleton to fuel migration and invasion, uncovering the decision-making processes of cells in response to nutrient availability through mechanisms like macropinocytosis. Machesky aims to create bioengineered platforms that simulate in vivo conditions to better study these dynamic processes. She has published extensively in esteemed journals, contributing notable findings that shed light on the mechanistic underpinnings of cancer cell behavior.
Standard postgraduate requirements for Department of Politics and International Studies (POLIS) and related humanities departments.