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Laura Pasqualucci, MD, is a Professor in the Department of Pathology and Cell Biology at Columbia University Irving Medical Center, specializing in the molecular pathogenesis of B cell malignancies, particularly diffuse large B cell lymphoma (DLBCL) and follicular lymphoma (FL). She earned her MD summa cum laude from the University of Perugia School of Medicine and completed her residency in Hematology. Dr. Pasqualucci's research employs multi-omics approaches, biochemical assays, and genetically engineered mouse models to uncover genetic alterations that drive cancers. She studies the tumor-suppressive roles of histone and chromatin modifiers such as KMT2D and CREBBP, identifying recurrent mutational targets in FL and DLBCL. Additionally, her work investigates the impact of non-coding mutations in super-enhancer regions on lymphoma pathogenesis, aiming to develop novel biomarkers and therapeutic strategies for B-cell lymphomas. She is an active member of several professional organizations, including the American Society of Hematology and the American Association for Cancer Research, and participates on various committees and advisory boards in her field.
Columbia University Irving Medical Center • New York, NY
Leading research in molecular pathogenesis of B cell malignancies.
Department of Anthropology (GSAS)