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Laurence Pelletier is a professor specializing in Molecular Genetics at the University of Toronto. His research focuses primarily on the intricacies of centrosome biology and its implications in cancer and developmental diseases. The Pelletier laboratory investigates the mechanisms by which centrosomes, composed of centriole pairs and the pericentriolar material (PCM), facilitate essential cellular functions such as bipolar mitotic spindle assembly and accurate chromosome segregation. Working with cutting-edge technologies, including advanced microscopy, biochemistry, and functional genomics, the lab aims to identify and study novel proteins essential for centrosome and cilia biogenesis. Key research themes include controlling centrosome duplication and assembly, ciliogenesis, cell signaling mechanisms, and the role of centrosomes in cell motility and metastasis.
Department of Sociology