Dr. Lawrence Brass

Biography

Lawrence F. Brass is a Professor in Medicine, specializing in Hematology-Oncology at the Perelman School of Medicine, University of Pennsylvania. He has a profound interest in the biology of platelets, particularly the mechanisms underlying thrombosis and hemostasis. His research focuses on understanding the clinical and biological responses of platelets in various vascular injuries and diseases. Brass employs advanced techniques including genetically engineered mouse models, high-resolution confocal microscopy, and systems biology approaches to study platelet activation and thrombus formation. He collaborates closely with various departments, including Medicine, Pediatrics, and Pharmacology, to explore the factors influencing platelet responses to vascular injury and the pathophysiological aspects of thrombosis. Throughout his career, he has contributed to significant advancements in the field of vascular biology and has been involved in multiple research projects funded by leading organizations such as the NIH and the American Heart Association. Brass is committed to educating the next generation of scholars in his laboratory, providing opportunities for rotations and thesis projects centered on these pivotal topics in biomedical research.

Research Interests