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Dr. Lawrence Young is a professor at the Yale School of Medicine specializing in cellular and molecular physiology with a focus on cardiovascular medicine. His research investigates the cellular and molecular mechanisms responsible for metabolic adaptation during hypoxic stress associated with myocardial ischemia. He is particularly interested in the AMP-activated protein kinase (AMPK) signaling pathway as a key regulator of glucose transporter (GLUT4) translocation, cellular metabolism, ion channel activity, and apoptosis in the heart. Dr. Young employs transgenic mouse models to dissect the role of AMPK signaling pathways in an intact perfused heart, aiming to develop innovative strategies to protect the heart from ischemic injury. He is also involved in studying cardiac signaling pathways and the impact of insulin resistance and diabetes on heart health.
Administered via the Graduate School of Arts and Sciences (GSAS). GRE General is optional for PhD.