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Dr. Lieping Chen is an immunologist focused on basic T cell biology and cancer immunology, emphasizing translational research to develop new treatments for human diseases, particularly cancer. He joined Yale School of Medicine after serving on the faculty at Johns Hopkins University School of Medicine and Mayo Clinic, and previously worked as a scientist at Bristol-Myers Squibb Pharmaceutical Research Institute. Over his career, Dr. Chen has published more than 400 peer-reviewed articles and led transformative studies, including the groundbreaking discovery of the PD-1/PD-L1 pathway, which has marked a significant innovation in cancer immunotherapy, recognized as the #1 breakthrough of 2013 by Science magazine. His laboratory continues to explore the dynamics of T cell co-stimulation and inhibition, contributing to a deeper understanding of tumor interactions with the immune system. With numerous accolades, including being a member of the National Academy of Sciences and a fellow of the American Association for Cancer Research, Dr. Chen's work remains central in the ongoing efforts to advance cancer treatment.
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