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Lillian J Eichner, PhD, is an Assistant Professor at Northwestern University Feinberg School of Medicine in the Department of Biochemistry and Molecular Genetics. Her research focuses on studying transcriptional dependencies in cancer development, progression, and resistance mechanisms. Lillian's work aims to elucidate in vivo transcriptional dependencies at the intersection of epigenetics, signaling, and metabolism, revealing therapeutically targetable transcriptional vulnerabilities in cancer. Specifically, she is investigating LKB1 (STK11) mutations in Non-Small Cell Lung Cancer (NSCLC), which are deactivated in approximately 20% of cases. By leveraging immune-competent genetically engineered mouse models, she has been able to uncover crucial insights into the molecular mechanisms driving this disease. Lillian's future research will continue to exploit mechanistic understanding to explore new transcriptional dependencies that could provide therapeutic liabilities in LKB1 mutant tumors. Her contributions have garnered her recognition, including the Early Career Researcher Year Award from the American Cancer Society and being named a V Scholar by the V Foundation.
Administered by The Graduate School; focuses on Biomechanics, Imaging, Biomaterials, and Regenerative Medicine.