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Lindsay Case studies how molecules concentrated in organized plasma membranes regulate transmembrane signaling. Her research focuses on the spatial organization of signaling molecules in the plasma membrane and how they control downstream signaling. For instance, she examines receptor clustering and the higher-order assembly of cytoplasmic proteins to create compartments with unique biochemical and biophysical properties. Her quantitative experimental approaches encompass biochemistry, molecular biophysics, and cell biology to investigate transmembrane signaling pathways that are misregulated in diseases such as cancer.
MIT Department of Biology • Cambridge, MA
Teaches and conducts research in molecular biophysics and cell biology, focusing on signal transduction.